Polypeptides in skincare: revolution for a youthful complexion

February 2024
The Derma Check AI

Written by


  • Type of ingredient: Peptide complexes
  • Main benefits: Promotes collagen production, smoothes fine lines, improves skin elasticity
  • Ideal for: Mature, ageing skin and to prevent signs of ageing
  • Frequency of use: Depending on product instructions, often daily
  • Combines well with: Antioxidants, hyaluronic acid, moisturizers
  • To be avoided with: Excessive use in combination with strong exfoliants

Introduction: What are polypeptides?

Polypeptides are small protein chains that consist of amino acids and are becoming increasingly popular in skin care. They are considered a miracle weapon against the signs of skin ageing.

Benefits of polypeptides for the skin

Promotion of collagen production

Polypeptides are known to stimulate collagen synthesis, resulting in firmer and tighter skin.

Reduction of fine lines and wrinkles

By strengthening the skin’s structure, polypeptides can reduce the appearance of fine lines and wrinkles.

Improvement of skin elasticity

Stimulating collagen production not only improves the appearance of the skin, but also its elasticity and firmness.

Possible side effects

Although polypeptides are generally well tolerated, they can cause skin irritation if used excessively or in combination with strong exfoliants.

Application of polypeptides in skin care

Correct application

  • Regular use: For best results, polypeptide-containing products should be used regularly.
  • Combination with moisturizer: Polypeptides work best in combination with moisturizing ingredients such as hyaluronic acid.

How not to use it

  • Avoid overuse: Excessive use, especially in combination with strong skin care products, should be avoided.


1. are polypeptides suitable for all skin types? Yes, polypeptides are generally suitable for all skin types, but especially for mature and ageing skin.

2. can polypeptides alone eliminate wrinkles? While polypeptides can improve the appearance of wrinkles, they are most effective when combined with a comprehensive skincare routine.

3. how quickly are results visible? Results may vary, but many users report visible improvements within a few weeks of regular use.


Polypeptides are a powerful ingredient in modern skincare that has the potential to significantly improve skin texture and reduce the signs of ageing. Regular use in combination with a balanced skin care routine can lead to a more youthful and firmer complexion. Experiment with polypeptide-containing products to experience the positive effects on your skin for yourself.

Was the article helpful?

AI Profile
The Derma Check AI
The Derma Check's AI has been trained with the help of numerous scientific studies. She specializes in cosmetic ingredients and their effects.